Description

• Chemical name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile;
• Formula: C₁₇H₁₁N₅
• Anabolic activity index: not a steroid
• Androgenic activity index: not a steroid

ULTIMA-FEMARA - ULTIMA PHARMACEUTICAL

50 pills, 5 mg/pill

Ultima-Femara is known as an aromatase inhibitor utilized in treating hormonally-responsive breast cancer post-surgery. It functions by blocking estrogen production, which is associated with a decrease in good cholesterol in the blood. This occurs because estrogen influences blood cholesterol levels, and its inhibition decreases good cholesterol. In brief, Letrozole, an anti-cancer medication, inhibits estrogen production in post-menopausal women diagnosed with breast cancer and reversibly inhibits aromatase. Moreover, Letrozole finds utility in bodybuilding and athletic circles for enhancing muscle mass and achieving a defined appearance.

Letrozole was discovered in the 1980s by scientists at the Swiss company Ciba-Geigy AG (now Novartis). It was described as more potent compared to other aromatase inhibitors. In 1996, Letrozole received approval from the U.S. Food and Drug Administration, marking its rapid development. Since the late 1990s, Letrozole has been widely used in treating various medical conditions.

Letrozole is identified as a non-steroidal inhibitor of estrogen synthesis, hindering the conversion of androgens to estrogen. Thus, Letrozole aids in treating cancers that depend on estrogen for growth stimulation. Additionally, it blocks estrogen synthesis in post-menopausal women and is integral to cancer therapies. Notably, Letrozole does not inhibit corticosteroid production in the body. Its molecular weight is 285.3 g/mol.

Medical Applications of Letrozole:

• Treatment of Breast Cancer: Approved by the FDA for treating hormone receptor-positive local breast cancer in post-menopausal women.
• Ovulation Induction: Prescribed by fertility doctors to stimulate ovulation and increase pregnancy chances.
• Management of Polycystic Ovary Syndrome (PCOS): Used to alleviate PCOS symptoms and possibly enhance fertility.
• Gynecomastia Treatment: Addresses abnormal breast growth in men, preventing potential malignancy.
• Spermatogenesis Promotion: Employed when semen lacks sperm.
• Endometriosis Treatment: Reduces estrogen levels in tumors, mitigating associated pain and symptoms.

Bodybuilding and Athletic Usage of Ultima-Femara: In addition to medical purposes, Letrozole is popular among bodybuilders and athletes. It aids in reducing estrogen levels, thereby minimizing anabolic steroid side effects. Furthermore, it enhances strength, reduces body fat, and improves muscle definition.

Benefits:

• Slows down the growth of certain cancer types.
• Reduces pain and symptoms associated with endometriosis.
• Enhances ovulation, increasing pregnancy chances.
• Reduces estrogen levels to mitigate anabolic steroid side effects.
• Improves strength, reduces body fat, and enhances muscle definition.

Side Effects of Letrozole: Common side effects include hot flashes, joint pain, night sweats, increased sweating, headache, fatigue, nausea, vomiting, thinning of hair, and weight gain. Less common side effects may include bone pain, muscle pain, bone loss, depression, anxiety, vision problems, high cholesterol, increased risk of infection, and increased risk of uterine cancer.

Dosage:

Letrozole is typically utilized during steroid cycles for estrogen control at a dosage of 0.5mg to 2.5mg per day. Duration of use depends on individual goals and steroid cycle duration, often used throughout the cycle. It's important to emphasize Letrozole usage under medical supervision.

Warnings:

• Be cautious of drug interactions with other medications or herbal supplements.
• Letrozole is suitable only for post-menopausal women.
• Avoid during breastfeeding due to potential transfer into breast milk.
• Pregnancy must be avoided during Letrozole treatment.
• Disclose medical history and current medications to healthcare providers to prevent allergic reactions or contraindications. Always inform about prescription and non-prescription medications, vitamins, supplements, or herbal products.