Loved the product, great efficacy. Will be ordering more because the first time was such a great experience. Packaging and shipping times were on point. Far better than purchasing research chems! Keep up the great quality, I will be a regular customer.
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ROAS (1 blister)
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$96.00
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Characteristics
ACTIVE HALF-LIFE
20-22 hours
Classification
Dermatotropic drug
Dosage
10-40 mg/day
ACNE
No
WATER RETENTION
No
HBR
No
HEPATOTOXICITY
Yes
AROMATIZATION
No
Active Substance
FORM
50 pills x 10 mg (1 blister)
Manufacturer
Description
- Chemical name: 13-cis retinoic acid
ROAS - PHARMACOM LABS
50 tabs x 10 mg (1 blister)
Isotretinoin, also known as 13-cis retinoic acid, is an oral pharmaceutical drug primarily utilized for acne treatment. In rare cases, it is prescribed to prevent certain skin cancers and for the treatment of other cancers, as well as addressing harlequin-type ichthyosis and lamellar ichthyosis. As a retinoid related to vitamin A, it occurs naturally in small quantities in the body.
Benefits:
- Amplifies production of neutrophil gelatinase-associated lipocalin (NGAL) in the skin, reducing sebum production and inducing apoptosis in sebaceous gland cells.
- Exhibits an antimicrobial effect on Propionibacterium acnes.
- Decreases the size and sebum output of sebaceous glands.
- Addresses all four major pathogenic processes in acne, distinguishing it from alternative treatments like antibiotics.
- Demonstrates efficacy, especially in severe nodulocystic cases.
Administration:
- Best absorbed when taken with a high-fat meal, doubling efficacy compared to fasting.
- Molecular resemblance to Vitamin A necessitates avoiding concurrent use with Vitamin A supplements due to the risk of cumulative overdosing.
Side Effects:
- Transient worsening of acne (lasting 2–3 weeks).
- Dry lips.
- Dry and fragile skin.
- Increased susceptibility to sunburn.
- Muscle aches and pains.
- Headaches.
Pregnancy-related Risks:
- Known to cause birth defects due to in utero exposure.
- Approximately 20%–35% risk for congenital defects in infants exposed to the drug in utero.
- About 30%–60% of children exposed to isotretinoin prenatally may exhibit neurocognitive impairment.
- Strict controls on prescribing isotretinoin to women who may become pregnant.
- Strongly advised for women who become pregnant while taking isotretinoin to terminate their pregnancies.
WARNING: DO NOT USE ISOTRETINOIN IF YOU ARE PREGNANT OR MAY BECOME PREGNANT!
Customer Reviews
03.10.2018
Accutanemane
Verified Purchase
28.09.2018
Lifesgood
Verified Purchase
After trying several other companies, PharmaComStore is hands down the best in terms of quality and service. And I can't complain about the shipping time as it is about the same as if I were to order from the US.
19.03.2018
J
Verified Purchase
Ive been using this accutane for approximately 5 weeks and notice my skin clearing up nicely , i started taking 20mg a day now that ive cleared up ive lowered to 10mg hoping that it keeps the acne away !!! Thanks
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